Small Molecule DNA and RNA Binders

Small Molecule DNA and RNA Binders
Author :
Publisher : John Wiley & Sons
Total Pages : 754
Release :
ISBN-10 : 9783527605668
ISBN-13 : 3527605665
Rating : 4/5 (665 Downloads)

Book Synopsis Small Molecule DNA and RNA Binders by : Martine Demeunynck

Download or read book Small Molecule DNA and RNA Binders written by Martine Demeunynck and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 754 pages. Available in PDF, EPUB and Kindle. Book excerpt: The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such as metal complexes, peptides, oligonucleotides and a wide array of synthetic organic compounds, is as manifold as the functions of nucleic acids. Nucleic acid recognition sequences are often found in the major or minor groove of a double strand, while other typical interactions include intercalation between base pairs or the formation of triple or quadruple helices. One example of a binding mode that has recently been proposed is end stacking on such complex structures as the telomere tetraplex. In this comprehensive book, internationally recognized experts describe in detail the important aspects of nucleic acid binding, and in so doing present impressive approaches to drug design. Since typical substances may be created naturally or synthetically, emphasis is placed on natural products, chemical synthesis, the use of combinatorial libraries, and structural characterization. The whole is rounded off by contributions on molecular modeling, as well as investigations into the way in which any given drug interacts with its nucleic acid recognition site.


Small Molecule DNA and RNA Binders Related Books

Small Molecule DNA and RNA Binders
Language: en
Pages: 754
Authors: Martine Demeunynck
Categories: Science
Type: BOOK - Published: 2006-03-06 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

The development of molecules that selectively bind to nucleic acids has provided many details about DNA and RNA recognition. The range of such substances, such
Small Molecule DNA and RNA Binders
Language: en
Pages: 732
Authors: Martine Demeunynck
Categories: Binding Sites
Type: BOOK - Published: 2003 - Publisher:

DOWNLOAD EBOOK

Small Molecule Microarrays: Methods and Protocols
Language: en
Pages: 274
Authors: Mahesh Uttamchandani
Categories: Science
Type: BOOK - Published: 2018-12-05 - Publisher: Methods in Molecular Biology

DOWNLOAD EBOOK

Artificial Assemblies with Cooperative DNA Recognition
Language: en
Pages: 145
Authors: Zutao YU
Categories: Science
Type: BOOK - Published: 2020-05-09 - Publisher: Springer Nature

DOWNLOAD EBOOK

This book presents three types of synthetically cooperative DNA recognizing assemblies, in order to advance the development of programmable DNA-binding pyrrole�
Long Non Coding RNA Biology
Language: en
Pages: 323
Authors: M.R.S. Rao
Categories: Medical
Type: BOOK - Published: 2017-08-16 - Publisher: Springer

DOWNLOAD EBOOK

This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. W