Numerical Methods for the Life Scientist
Author | : Heino Prinz |
Publisher | : Springer Science & Business Media |
Total Pages | : 155 |
Release | : 2011-08-06 |
ISBN-10 | : 9783642208201 |
ISBN-13 | : 3642208207 |
Rating | : 4/5 (207 Downloads) |
Download or read book Numerical Methods for the Life Scientist written by Heino Prinz and published by Springer Science & Business Media. This book was released on 2011-08-06 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Enzyme kinetics, binding kinetics and pharmacological dose-response curves are currently analyzed by a few standard methods. Some of these, like Michaelis-Menten enzyme kinetics, use plausible approximations, others, like Hill equations for dose-response curves, are outdated. Calculating realistic reaction schemes requires numerical mathematical routines which usually are not covered in the curricula of life science. This textbook will give a step-by-step introduction to numerical solutions of non-linear and differential equations. It will be accompanied with a set of programs to calculate any reaction scheme on any personal computer. Typical examples from analytical biochemistry and pharmacology can be used as versatile templates. When a reaction scheme is applied for data fitting, the resulting parameters may not be unique. Correlation of parameters will be discussed and simplification strategies will be offered.