Molecular Mechanisms in the Control of Gene Expression

Molecular Mechanisms in the Control of Gene Expression
Author :
Publisher : Elsevier
Total Pages : 668
Release :
ISBN-10 : 9781483273938
ISBN-13 : 1483273938
Rating : 4/5 (938 Downloads)

Book Synopsis Molecular Mechanisms in the Control of Gene Expression by : Donald P. Nierlich

Download or read book Molecular Mechanisms in the Control of Gene Expression written by Donald P. Nierlich and published by Elsevier. This book was released on 2013-10-22 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Mechanisms in the Control of Gene Expression documents the proceedings of the ICN-UCLA conference on Molecular Mechanisms in the Control of Gene Expression, organized through the Molecular Biology Institute of UCLA, held in Keystone, Colorado, 21-26 March 1976. The conference focused on three topics: the action of repressors on specific nucleotide sequences in DNA; how DNA and histones are intertwined in eucaryotic chromosomes; and in the development of new techniques that appear to lift genes from complex genomes. The volume contains 65 chapters organized into nine parts. The papers in Part I examine the organization of prokaryotic and eukaryotic chromosomes. Part II presents studies on the interaction of RNA a polymerase and regulatory molecules with defined DNA sites. Parts III and IV focus on RNA polymerases of eukaryotes and the regulation of transcription in eukaryotic systems, respectively. Part V contains papers dealing with nucleic acid sequences, transcription, and processing. Part VI covers cellular aspects in the study of gene expression. Part VII takes up cloning while Part VIII is devoted to genetic analysis through restriction mapping and molecular cloning. Finally, Part IX summarizes the recent progress reported at the conference and also indicates some of the limitations that can be placed upon interpretation of data.


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The use of molecular biology and biochemistry to study the regulation of gene expression has become a major feature of research in the biological sciences. Many