Download or read book Notch Signaling Guides Vascular Smooth Muscle Cell Function written by Ning Zhao and published by . This book was released on 2014 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Abstract: Proper blood vessel formation and function is crucial for embryogenesis, wound healing, pregnancy and diseases. The interaction of endothelial cells and vascular smooth muscle cells/pericytes is critical for assembling and maintaining blood vessels. Previously, our lab and other groups showed that endothelial cells play an important role in governing vascular smooth muscle cell functions. To further investigate the signaling mechanisms that govern the interaction of vascular cells, we screened for genes and microRNAs whose expression was significantly altered by the endothelial cell-smooth muscle cell interaction.