Integrated Strategies for Drug Discovery Using Mass Spectrometry

Integrated Strategies for Drug Discovery Using Mass Spectrometry
Author :
Publisher : John Wiley & Sons
Total Pages : 576
Release :
ISBN-10 : 9780471721024
ISBN-13 : 0471721026
Rating : 4/5 (026 Downloads)

Book Synopsis Integrated Strategies for Drug Discovery Using Mass Spectrometry by : Mike S. Lee

Download or read book Integrated Strategies for Drug Discovery Using Mass Spectrometry written by Mike S. Lee and published by John Wiley & Sons. This book was released on 2005-09-02 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: New strategies and techniques for today's fast-paced discoveryprocess Today, the pressure is on for high-throughput approaches toaccelerate the generation, identification, and optimization ofmolecules with desirable drug properties. As traditional methods ofanalysis become antiquated, new analytical strategies andtechniques are necessary to meet sample throughput requirements andmanpower constraints. Among them, mass spectrometry has grown to bea front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometryprovides a thorough review of current analytical approaches,industry practices, and strategies in drug discovery. The topicsrepresent current industry benchmarks in specific drug discoveryactivities that deal with proteomics, biomarker discovery,metabonomic approaches for toxicity screening, lead identification,compound libraries, quantitative bioanalytical support,biotransformation, reactive metabolite characterization, leadoptimization, pharmaceutical property profiling, sample preparationstrategies, and automation. THIS BOOK: * Clearly explains how drug discovery and mass spectrometry areinterconnected * Discusses the uses and limitations of various types of massspectrometry in various aspects of drug discovery * Prominently features analytical applications that requiretrace-mixture analysis * Provides industry applications and real-world examples * Shares historical background information on various techniques toaid in the understanding of how and why new methods are now beingemployed to analyze samples


Integrated Strategies for Drug Discovery Using Mass Spectrometry Related Books

Integrated Strategies for Drug Discovery Using Mass Spectrometry
Language: en
Pages: 576
Authors: Mike S. Lee
Categories: Science
Type: BOOK - Published: 2005-09-02 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

New strategies and techniques for today's fast-paced discoveryprocess Today, the pressure is on for high-throughput approaches toaccelerate the generation, iden
Proteomics for Drug Discovery
Language: en
Pages: 0
Authors: Iulia M. Lazar
Categories: Medical
Type: BOOK - Published: 2018-08-03 - Publisher: Humana

DOWNLOAD EBOOK

This book reflects the drug development community’s interest in proteomics methods by providing researchers with the necessary knowledge for the implementatio
Mass Spectrometry in Medicinal Chemistry
Language: en
Pages: 460
Authors: Klaus Wanner
Categories: Science
Type: BOOK - Published: 2007-06-27 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

This first overview of mass spectrometry-based pharmaceutical analysis is the key to improved high-throughput drug screening, rational drug design and analysis
Characterization of Protein Therapeutics using Mass Spectrometry
Language: en
Pages: 408
Authors: Guodong Chen
Categories: Science
Type: BOOK - Published: 2014-07-08 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

This book highlights current approaches and future trends in the use of mass spectrometry to characterize protein therapies. As one of the most frequently utili
Mass Spectrometry in Drug Discovery
Language: en
Pages: 436
Authors: David T. Rossi
Categories: Medical
Type: BOOK - Published: 2001-11-07 - Publisher: CRC Press

DOWNLOAD EBOOK

Mass Spectrometry in Drug Discovery summarizes the theory, instrumentation, techniques, and application of mass spectrometry and atmospheric pressure ionization