Dose-Response Analysis Using R

Dose-Response Analysis Using R
Author :
Publisher : CRC Press
Total Pages : 227
Release :
ISBN-10 : 9781351981040
ISBN-13 : 1351981048
Rating : 4/5 (048 Downloads)

Book Synopsis Dose-Response Analysis Using R by : Christian Ritz

Download or read book Dose-Response Analysis Using R written by Christian Ritz and published by CRC Press. This book was released on 2019-07-19 with total page 227 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, environmental sciences, genetics, pharmacology, plant sciences, toxicology, and zoology. In the 1940 and 1950s, dose-response analysis was intimately linked to evaluation of toxicity in terms of binary responses, such as immobility and mortality, with a limited number of doses of a toxic compound being compared to a control group (dose 0). Later, dose-response analysis has been extended to other types of data and to more complex experimental designs. Moreover, estimation of model parameters has undergone a dramatic change, from struggling with cumbersome manual operations and transformations with pen and paper to rapid calculations on any laptop. Advances in statistical software have fueled this development. Key Features: Provides a practical and comprehensive overview of dose-response analysis. Includes numerous real data examples to illustrate the methodology. R code is integrated into the text to give guidance on applying the methods. Written with minimal mathematics to be suitable for practitioners. Includes code and datasets on the book’s GitHub: https://github.com/DoseResponse. This book focuses on estimation and interpretation of entirely parametric nonlinear dose-response models using the powerful statistical environment R. Specifically, this book introduces dose-response analysis of continuous, binomial, count, multinomial, and event-time dose-response data. The statistical models used are partly special cases, partly extensions of nonlinear regression models, generalized linear and nonlinear regression models, and nonlinear mixed-effects models (for hierarchical dose-response data). Both simple and complex dose-response experiments will be analyzed.


Dose-Response Analysis Using R Related Books

Dose-Response Analysis Using R
Language: en
Pages: 227
Authors: Christian Ritz
Categories: Mathematics
Type: BOOK - Published: 2019-07-19 - Publisher: CRC Press

DOWNLOAD EBOOK

Nowadays the term dose-response is used in many different contexts and many different scientific disciplines including agriculture, biochemistry, chemistry, env
Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R
Language: en
Pages: 285
Authors: Dan Lin
Categories: Mathematics
Type: BOOK - Published: 2012-08-27 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

This book focuses on the analysis of dose-response microarray data in pharmaceutical settings, the goal being to cover this important topic for early drug devel
Nonlinear Regression with R
Language: en
Pages: 151
Authors: Christian Ritz
Categories: Mathematics
Type: BOOK - Published: 2008-12-11 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

- Coherent and unified treatment of nonlinear regression with R. - Example-based approach. - Wide area of application.
Science and Decisions
Language: en
Pages: 422
Authors: National Research Council
Categories: Political Science
Type: BOOK - Published: 2009-03-24 - Publisher: National Academies Press

DOWNLOAD EBOOK

Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has be
10 Steps to Develop Great Learners
Language: en
Pages: 168
Authors: John Hattie
Categories: Education
Type: BOOK - Published: 2022-04-07 - Publisher: Routledge

DOWNLOAD EBOOK

What can concerned parents and carers do to ensure their children, of all ages, develop great learning habits which will help them achieve their maximum at scho