Patch-Clamp Methods and Protocols

Patch-Clamp Methods and Protocols
Author :
Publisher : Springer Science & Business Media
Total Pages : 319
Release :
ISBN-10 : 9781603270908
ISBN-13 : 1603270906
Rating : 4/5 (906 Downloads)

Book Synopsis Patch-Clamp Methods and Protocols by : Peter Molnar

Download or read book Patch-Clamp Methods and Protocols written by Peter Molnar and published by Springer Science & Business Media. This book was released on 2007 with total page 319 pages. Available in PDF, EPUB and Kindle. Book excerpt: Patch Clamp Methods and Protocols surveys the typical patch clamp applications and advises scientists on identifying problems and selecting the best technique in each instance. The experiments described require a basic level of electrophysiological training and aid the researcher in pursuing new areas of electrophysiology and using the patch clamp technique effectively. Patch Clamp Methods and Protocols is divided into three sections that cover the major areas of patch clamp application: Pharmacology, Physiology, and Biophysics. The first section provides examples and step by step instructions on how to use whole-cell and single-channel patch clamp methods for testing drugs in industrial settings. The second section provides a wide selection of patch clamp applications in physiological studies. The last part focuses on the biophysical applications of the patch clamp method using single channel recordings or statistical analysis of whole-cell currents in order to obtain parameters that describe ion channel properties or transmitter release. Individual techniques are explored within the area that they are applied most often. Researchers will find Patch Clamp Methods and Protocols to be an invaluable aid in the design and execution of a wide variety of patch clamp experiments, both on their own and in conjunction with other state-of-the-art methodologies.


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