Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis

Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis
Author :
Publisher : Springer Science & Business Media
Total Pages : 289
Release :
ISBN-10 : 9788847021174
ISBN-13 : 8847021170
Rating : 4/5 (170 Downloads)

Book Synopsis Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis by : O.R. Hommes

Download or read book Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis written by O.R. Hommes and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: There is now evidence that irreversible brain damage accumulates very early in the course of multiple sclerosis. This book reviews the main neurobiological, magnetic resonance imaging, and clinical aspects of the early phases of the dis ease. Mechanisms ofirreversible axonal damage and the role played by the inter action of glia and the axon are highlighted. In contrast to what was believed for a long time, the sufficient availability of oligodendrocyte precursor cells to promote remyelination in acute lesions has now been demonstrated. For reasons not understood, this remyelination process fails or does not start, particularly in the chronic stages ofthe disease. These findings emphasize the importance of the "milieu" changes induced by an inflammatory process in limiting remyelination. However, first indications are that part of this inflammatory process may have a neuroprotective effect. Pathological studies in multiple sclerosis have now clearly demonstrated that destructive processes may be followed by recovery phases in such a way that myelin may be morphologically and functionally reconstituted. These findings provide the rationale for early treatment and emphasize the importance of clinical trials in early multiple sclerosis. Early treatment is one of the most important aspects in multiple sclerosis today.


Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis Related Books

Neuroprotective Mechanisms in Multiple Sclerosis
Language: en
Pages: 106
Authors: Svenja Zietzling
Categories:
Type: BOOK - Published: 2009 - Publisher:

DOWNLOAD EBOOK

Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis
Language: en
Pages: 289
Authors: O.R. Hommes
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

There is now evidence that irreversible brain damage accumulates very early in the course of multiple sclerosis. This book reviews the main neurobiological, mag
Myelin Repair and Neuroprotection in Multiple Sclerosis
Language: en
Pages: 296
Authors: Ian D. Duncan
Categories: Medical
Type: BOOK - Published: 2012-08-31 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Myelin Repair and Neuroprotection in Multiple Sclerosis presents an up-date on the translational potential of promoting remyelination in multiple sclerosis (MS)
Mechanisms of Neuroprotection and Remyelination in Demyelinating Disease Models of Multiple Sclerosis: A Lesson From Estrogen Receptor Specific Ligands
Language: en
Pages: 154
Authors: Youn-Jung Roy Kim
Categories:
Type: BOOK - Published: 2018 - Publisher:

DOWNLOAD EBOOK

Currently, available drugs for multiple sclerosis (MS) are predominantly immune-modulatory. They are effective in reducing relapses, but not in slowing down or
Multiple Sclerosis
Language: en
Pages: 137
Authors: Ian S. Zagon
Categories:
Type: BOOK - Published: 2017 - Publisher:

DOWNLOAD EBOOK